The Summer Undergraduate Research Fellowship/L&S program (SURF/L&S) allows UC Berkeley undergraduates in the College of Letters and Science to spend the summer doing concentrated research in preparation for a senior thesis. About forty fellows will be funded in 2014, receiving $4250. Please fill out the eligibility screen here so we can guide you.
In addition to receiving funding, each summer fellow will be assigned to a research cluster, which will meet weekly throughout the summer. In the cluster you will find a community of undergraduate researchers with similar interests and problems, as well as a cluster mentor, an experienced researcher to help... more
Mycobacterium tuberculosis manipulates the host response to prevent bactericidal mechanisms and promote its own survival. AKT is one enzyme that has been linked to proliferation of M. tuberculosis within its target. As a serine/threonine protein kinase, AKT is an important enzyme in signal transduction pathways for apoptosis. Inhibition of AKT during infection leads to increase bacterial death. By looking at the downstream effects of the AKT pathway, our goal is to determine, “why?” This will be accomplished by using site directed mutagenesis to create multiple alterations to the structure of AKT in macrophages and then using inhibitors of AKT, stop the downstream effects at numerous junctures after being infected by a model organism, M. Smegmatis. Western blotting will be used to... Read More