Interspecies Interactions Resulting in Induced Antibiotic Production

Summer 2017

Yein Ra : Microbial Biology and MCB, Biochemistry

Mentor: Matthew Traxler

Bacteria that make up the soil microbial community are a significant source of natural antibiotics. In particular, species of Streptomyces are well known for their capability to produce a plethora of antibiotics, and it has been observed that the production of these antibiotics is accelerated when Streptomyces is interacting with certain neighboring microbes. We have found that compared to other soil microbes, Arthrobacter species can more robustly induce antibiotic formation in Streptomyces. I am investigating the mechanism of how the interactions between species of Arthrobacter and Streptomyces result in enhanced antibiotic production, and I aim to determine a method that optimizes natural antibiotic production in Streptomyces species by studying these complex relationships.

I would not be able to dedicate myself full-time to this project if I didn’t receive the support from the Rose Hills Foundation. Thus, I would like to thank the Rose Hills Foundation for allowing me to pursue research this summer.